Antiparietal cell antibody test

定义

An antiparietal cell antibody test is a blood test that looks for 抗体 against the parietal cells of the stomach. The parietal cells make and release a substance that the body needs to absorb vitamin B12.

Alternative Names

APCA; Anti-gastric parietal cell antibody; 萎缩性 胃炎 - anti-gastric parietal cell antibody; 胃溃疡 - anti-gastric parietal cell antibody; Pernicious anemia - anti-gastric parietal cell antibody; Vitamin B12 - anti-gastric parietal cell antibody

How the Test is Performed

A 血液样本 是必要的.

How to Prepare for the Test

No special preparation is necessary.

How the Test will Feel

When the needle is inserted to draw blood, some people feel moderate pain. Others feel only a prick or stinging. Afterward, there may be some throbbing or slight bruising. This soon goes away.

Why the Test is Performed

Your health care provider may use this test to help diagnose pernicious anemia. Pernicious anemia is a decrease in red blood cells that occurs when your intestines cannot properly absorb vitamin B12. Other tests are also used to help with the diagnosis.

正常的结果

A normal result is called a negative result.

Normal value ranges may vary slightly among different laboratories. Some labs use different measurements or test different samples. Talk to your provider about the meaning of your specific test results.

What Abnormal Results Mean

An abnormal result is called a positive result. This may be due to:

• 萎缩性 胃炎 (inflammation of the stomach lining)
• 糖尿病
• 胃溃疡
• 甲状腺疾病

风险

There is little risk involved with having your blood taken. Veins and arteries vary in size from one person to another, and from one side of the body to the other. Taking blood from some people may be more difficult than from others.

Other risks associated with having blood drawn are slight, but may include:

• Excessive bleeding
• Fainting or feeling lightheaded
• Multiple punctures to locate veins
• Hematoma (blood buildup under the skin)
• Infection (a slight risk any time the skin is broken)

参考文献

Cooling LL, Downs T. 免疫血液学. In: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. 24日艾德. Philadelphia, PA: Elsevier; 2022:chap 36.

Höegenauer C, Hammer HF. Maldigestion and malabsorption. In: Feldman M, Friedman LS, Brandt LJ, eds. Sleisenger and Fordtran's Gastrointestinal and Liver Disease. 11日艾德. Philadelphia, PA: Elsevier; 2021:chap 104.

Marcogliese AN, Yee DL. Resources for the hematologist: interpretive comments and selected reference values for neonatal, 儿科, and adult populations. In: Hoffman R, Benz EJ, Silberstein LE, et al, eds. Hematology: Basic Principles and Practice. 7日艾德. Philadelphia, PA: Elsevier; 2018:chap 162.