Gastroenterology

Nonalcoholic 高脂肪的 肝 疾病

Overview

Nonalcoholic fatty liver disease (NAFLD), also known as steatohepatitis, 肝脏炎症是由肝脏组织中脂肪堆积引起的吗. In most people, the underlying problem is 肥胖, 糖尿病 或两个. 其他因素包括糖尿病家族史和非肥胖人群的高血脂. 在一些患者中，遗传因素似乎很重要.

NAFLD通常在肝功能检查中表现为意想不到的异常, usually the alanine aminotransferase (ALT) test, in people who otherwise feel well. 这项测试的升高通常是轻微的，在年轻的患者中, does not indicate a serious liver condition. 然而, if the cause of NAFLD, such as 肥胖 or 糖尿病, is not treated, the condition may progress.

在50岁以上的人群中，NAFLD的第一个症状可能是严重肝病的征兆， 肝硬化. Studies are underway to determine the precise risk of progression of NAFLD to 肝硬化; at this time, it is estimated as 20 percent.

随着肥胖在美国的流行率不断上升, the incidence of NAFLD also has been increasing. 因此，NAFLD现在是患者转诊的最常见原因之一 liver transplantation.

Our Approach to Nonalcoholic 高脂肪的 肝 疾病

治疗非酒精性脂肪性肝病的重点是解决其根本原因, which is often 肥胖, 糖尿病 或两个. Successful treatment can stop or slow the liver damage.

如果肝脏受损严重，无法发挥功能，肝移植可能是一种选择. 加州大学旧金山分校提供肝脏移植项目，以其出色的结果和生存统计数据而闻名，在全国名列前茅. 我们的项目帮助开创了使移植更安全、更成功的技术.

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迹象 & 症状

非酒精性脂肪性肝病(NAFLD)的体征和症状差异很大, depending on the stage of the condition. During the early or middle stages of the disease, 患者通常没有与肝脏疾病直接相关的症状. 然而，随着病情的发展，患者可能会出现肝硬化的症状，包括:

  • 乏力
  • Memory loss or confusion
  • Fluid retention in the abdomen or legs
  • 带柏油的黑便，表明有内出血

诊断

非酒精性脂肪性肝病(NAFLD)通常是偶然发现的, as part of testing for an unrelated problem. 以下检查可用于确诊:

  • Blood Tests 将进行血液检查，测量整体肝功能并指示炎症活动, along with additional blood tests to exclude viral hepatitis.
  • 肝 Ultrasound 这是一个 simple imaging procedure 检查肝脏形状和稠度的不规则性以及胆道的问题, such as gallstones.
  • Computed Tomography (CT) Computed tomography (CT) 是一种用细x射线束围绕病人旋转的身体成像方法吗, to provide a detailed view of the liver.
  • 肝 Biopsy In some cases, a liver biopsy may be needed to make a definite diagnosis of NAFLD. 该测试还有助于确定疾病的阶段和肝脏炎症的严重程度. During the biopsy, 哪一种是门诊手术，在局部麻醉下进行, 将一根针插入肝脏以获得一个小样本.

Treatments

目前, 肥胖和/或血脂(脂肪)升高的NAFLD患者的治疗目标是减轻体重. 那些血糖控制不好的糖尿病患者应该与糖尿病专家和营养师一起控制血糖. All patients with NAFLD should avoid alcohol.

NAFLD的治疗正在不断发展，并在各种研究中得到严格的调查. 加州大学旧金山分校正在十大赌博靠谱网络平台一项研究NAFLD和新疗法的大型试验.

肝 Transplantation

在某些情况下，NAFLD可能发展为肝功能衰竭，需要 liver transplantation. 移植的评估很复杂，通常需要几个月的时间. 因此, 即使患者感觉良好，也应该在出现肝功能衰竭的第一个迹象时，或者通过x光检查或肝活检诊断出患有晚期肝病时，进行移植手术.

加州大学旧金山分校健康医学专家已经审查了这些信息. 它仅用于教育目的，并不打算取代您的十大赌博平台排行榜或其他医疗保健提供者的建议. 我们鼓励您与您的供应商讨论您可能遇到的任何问题或疑虑.

More treatment info

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